Comparative Genomics

JCVI: A Versatile Toolkit for Comparative Genomics Analysis

The life cycle of genome builds spans interlocking pillars of assembly, annotation, and comparative genomics to drive biological insights. While tools exist to address each pillar …

haibao-tang

Chromosome-Level Scaffolding of Haplotype-Resolved Assemblies Using Hi-C Data without Reference Genomes

Scaffolding is crucial for constructing most chromosome-level genomes. The high- throughput chromatin conformation capture (Hi-C) technology has become the primary scaffolding …

xiaofei-zeng

A Chromosomal-Scale Genome Assembly of Modern Cultivated Hybrid Sugarcane Provides Insights into Origination and Evolution

Sugarcane is a vital crop with significant economic and industrial value. However, the cultivated sugarcane's ultra-complex genome still needs to be resolved due to its high ploidy …

yixue-bao